PHOSPHOGAM

PhosphoGam has developed the technology to manufacture nearly limitless numbers of gamma/delta T-cells obtained from healthy donors. These universal killer cells can be generated at a fraction of the cost of other cell therapies, including CAR T cells, and can be used against a multitude of cancers without need for artificial targeting.
 

PhosphoGam's Unique Approach

PhosphoGam's unique proprietary cell manufacturing capabilities — combined with our revolutionary clinical delivery platform — allows us to exploit the broad, innate antitumor properties of unmodified human gamma/delta-T cells derived from the blood of healthy allogeneic donors.

The PhosphoGam technology platform has been designed and optimized to exclusively stimulate the the Vd2+ type of gamma/delta-T cells. PhosphoGam is the only company able to economically generate essentially limitless numbers of highly pure universal killer Vd2+ gamma/delta-T cells in a simple, scaleable process that does not require costly purification steps.

Key to the allogeneic therapeutic strategy is that PhosphoGam ex vivo expanded unmodified Vd2+ gamma/delta-T cells retain their innate ability to recognize and kill virtually any type of malignant cell — and do so without need of costly and complicated genetic modifications such as those required to generate CAR T cells.

Generating essentially limitless numbers of universal killer allogeneic T cells ready at anytime for off-the-shelf use can enable a revolution in cancer cell therapy. PhosphoGam's simple and elegant approach offers significant biological and economic advantages over all artificially-targeted cell therapies, including allogeneic CAR T cells.